Mandava confirmed that the tournament in Morocco would be his last with the Mambas after Mozambique were beaten 40 by Nigeria in the last-16 tie on Tuesday in Fes. The defeat marked the end of a historic campaign and also signalled the international farewell of long-serving captain Dominguez and experienced defender Mexer Site.
Despite the heavy scoreline against one of Africas most powerful sides, the trios departure has been framed as the close of a cycle that transformed Mozambican football.
Mandava, one of the most influential players of his generation, addressed teammates in an emotional moment, describing his decision as an act of responsibility and love for the national team, and a chance for younger players to step forward.
The Sunderland midfielder has been central to Mozambiques resurgence on the continental stage, praised for his leadership, consistency and professionalism both on and off the pitch.
This was my last match, my last campaign, Mexer said, confirming the decision had been discussed earlier with Mandava and Dominguez. Now it is time to give strength to the younger ones. The national team will always be in my heart.
Captain Dominguez, who led Mozambique through some of its most challenging and rewarding years, offered only a brief but deeply emotional farewell, expressing gratitude after a lifetime of service.
Head coach Chiquinho Conde described the moment as one of the most difficult of his tenure.
It is a hard blow like losing a member of the family, he said. More than players, they are men who shaped this group. Everything I know as a coach, I learned with them.
The Mozambican Football Federation paid tribute to the trio, with vice-president Paito Mucuana saying the country was sad, but deeply proud of what the team had achieved. He also appealed to Mandava to reconsider his decision, highlighting his age and symbolic importance to the squad.
Dominguez, Mexer and Mandava leave as three captains of a generation that returned Mozambique to the Africa Cup of Nations, challenged established powers and restored belief at home.
Their international careers end with defeat in Fes, but their legacy of commitment, unity and ambition is expected to shape the national team for years to come.