Springboks will take to the Loftus Versfeld pitch on Saturday against Italy with centre Jesse Kriel as their captain, making him the 67th player to skipper the Boks in a test match.
Regular captain Siya Kolisi is ruled out through stiffness - first in the neck and then the Achilles tendon - picked up last week.
Vincent Tshituka will earn his first test cap at flank, after impressing against the Barbarians last week.
Fullback Damian Willemse returns for the first time since the World Cup final of 2023, while scrumhalf Faf de Klerk is on the bench.
The Boks are preparing to face Italy in the first of two test matches that constitute the Incoming tour with the final test being against Georgia.
