Liverpool and Arsenal aim to strike first blood in the Premier League title race as last seasons top two face off at Anfield after a summer of heavy spending.
Manchester Uniteds investment in a new forward line is yet to reap any reward, heaping the pressure on Ruben Amorim to deliver when Burnley visit Old Trafford.
However, it is West Hams Graham Potter and Nottingham Forest boss Nuno Espirito Santo who have the shortest odds on being the first Premier League manager to be sacked ahead of their meeting at the City Ground.